What Is CMV Negative?

Are you curious to know what is CMV negative? You have come to the right place as I am going to tell you everything about CMV negative in a very simple explanation. Without further discussion let’s begin to know what is CMV negative?

What Is CMV Negative?

CMV, or cytomegalovirus, is a common virus that affects many people. However, for certain individuals, being CMV negative is important for their health and wellbeing. In this blog post, we’ll explore what it means to be CMV negative, why it matters, and how it can impact different populations.

What Is CMV?

CMV is a type of herpes virus that can cause a range of symptoms, from mild to severe. Most people who are infected with CMV show no symptoms, but in some cases, it can cause flu-like symptoms, fatigue, and muscle aches. In rare cases, it can lead to serious health complications, particularly in people with weakened immune systems.

What Does It Mean To Be CMV Negative?

Being CMV negative means that a person has not been infected with CMV. This can be determined through a blood test that looks for the presence of CMV antibodies. CMV negative individuals do not have the virus in their system and have not developed immunity to it.

Why Does CMV Status, Matter?

For most people, CMV status is not a significant concern. However, for certain populations, being CMV negative is important for their health and wellbeing. This includes:

  • Pregnant Women: CMV infection during pregnancy can be dangerous for both the mother and the developing fetus. If a pregnant woman contracts CMV for the first time during pregnancy, there is a risk of miscarriage, stillbirth, or birth defects. For this reason, women who are planning to become pregnant or are pregnant are often tested for CMV status.
  • Transplant Recipients: Individuals who receive an organ transplant are at risk for CMV infection, particularly if the donor was CMV positive. CMV can cause serious complications in transplant recipients, including pneumonia and organ failure.
  • Immunocompromised Individuals: People with weakened immune systems, such as those with HIV/AIDS or undergoing chemotherapy, are at a higher risk for CMV infection and its complications.


CMV negative status is an important consideration for certain populations, including pregnant women, transplant recipients, and immunocompromised individuals. While most people who are infected with CMV show no symptoms, the virus can lead to serious complications in some cases. Understanding CMV and its impact on different populations is important for maintaining good health and wellbeing.

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What Does CMV Status Mean?

CMV stands for cytomegalovirus. It is a common virus that can infect anyone, anytime. Donors who have had a CMV infection, but not an active one during the time of donation, will have a positive (+) CMV status. Sperm donors who have never had a CMV infection will have a negative (-) CMV status.

How Do You Get CMV?

CMV is spread from an infected person in the following ways: From direct contact with saliva or urine, especially from babies and young children. Through sexual contact. From breast milk to nursing infants.

Do You Want To Be CMV Positive Or Negative?

Recommendations for choosing sperm for donor IUI

Those women who have had a past infection are at very low risk of transmitting CMV infection to as fetus. They are at little to no risk from using a CMV positive donor. Women who have never been exposed to CMV however, should consider using a CMV negative sperm donor.

What Are CMV Negative Products?

CMV negative blood components are those collected from donors who have been tested and found negative for CMV IgG antibodies. A proportion of donations are screened by the blood services for CMV IgG antibodies to provide a ‘CMV negative’ inventory for red cells and platelets, which are provided to hospitals on request.


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